News

New EVIMalaR publication in Scientific Reports

Thursday, 02 May 2013

Menard Lab Publication

Role of host cell traversal by the malaria sporozoite during liver infection.

Plasmodium is transmitted to a mammalian host during the bite by an infected anopheline mosquito. The sporozoite form of the parasite is injected into the skin and eventually reaches the liver, where it invades a hepatocyte inside a vacuole and transforms into thousands of red blood cell-infective forms. To access the liver parenchyma and hepatocytes, the sporozoite thus needs to cross the liver sinusoidal barrier.

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New EVIMalaR publication in Scientific Reports

Wednesday, 01 May 2013

Kwiatowski Lab Publication

Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia.

“Our survey of genetic variation showed that Western Cambodian malaria parasites had a population structure that was strikingly different to those of the other countries we analysed. Different not just from countries in Africa, but also different from malaria parasite populations in neighbouring Thailand, Vietnam, and even Eastern Cambodia,” says Professor Dominic Kwiatkowski, senior author of the paper from the Wellcome Trust Sanger Institute and University of Oxford.

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New EVIMalaR publication in Scientific Reports

Thursday, 25 April 2013

Chitnis Lab Publication

Calcium-dependent permeabilization of erythrocytes by a perforin-like protein during egress of malaria parasites.

The blood stage of Plasmodium falciparum is responsible for the high morbidity and mortality associated with malaria. In this stage, P. falciparum merozoites invade red blood cells (RBC), replicate and exit from the host cell upon maturation. Released merozoites go on to reinvade uninfected RBCs and continue their life cycle. Egress of P. falciparum merozoites from mature schizonts requires the timely rupture of the host cell membrane through a highly regulated and active process.

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Comic Relief 2013 – Malaria Efforts

Monday, 08 April 2013

This year for Red Nose Day, the EVIMalaR office teamed up with others in Glasgow University to help raise money for Comic Relief! This included a bake sale, a raffle and book donations. Our efforts helped raise £179.00 which contributed towards the £75,107,851 raised so far.

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