Publications 2011
December 2011
Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility.
Laurentino EC, Taylor S, Mair GR, Lasonder E, Bartfai R, Stunnenberg HG, Kroeze H, Ramesar J, Franke-Fayard B, Khan SM, Janse CJ, Waters AP.
PMID:21899698[PubMed - indexed for MEDLINE]
Lack of significant influence for Fc?RIIa-RH131 or hemoglobin AA/AS polymorphisms on immunity and susceptibility to uncomplicated malaria and existence of marked linkage between the two polymorphisms in Daraweesh.
Giha HA, Nasr A, Iriemenam NC, Troye-Blomberg M, Berzins K, Elghazali G.
PMID:22289203 [PubMed - as supplied by publisher]
Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility.
Laurentino EC, Taylor S, Mair GR, Lasonder E, Bartfai R, Stunnenberg HG, Kroeze H, Ramesar J, Franke-Fayard B, Khan SM, Janse CJ, Waters AP.
PMID:21899698 [PubMed - in process]
Stage-specific depletion of myosin A supports an essential role in motility of malarial ookinetes.
Siden-Kiamos I, Ganter M, Kunze A, Hliscs M, Steinbüchel M, Mendoza J, Sinden RE, Louis C, Matuschewski K.
PMID:21899701 [PubMed - in process]
November 2011
Global kinomic and phospho-proteomic analyses of the human malaria parasite Plasmodium falciparum.
Solyakov L, Halbert J, Alam MM, Semblat JP, Dorin-Semblat D, Reininger L, Bottrill AR, Mistry S, Abdi A, Fennell C, Holland Z, Demarta C, Bouza Y, Sicard A, Nivez MP, Eschenlauer S, Lama T, Thomas DC, Sharma P, Agarwal S, Kern S, Pradel G, Graciotti M, Tobin AB, Doerig C.
PMID:22127061[PubMed - in process]
A critical role of perinuclear filamentous actin in spatial repositioning and mutually exclusive expression of virulence genes in malaria parasites.
Zhang Q, Huang Y, Zhang Y, Fang X, Claes A, Duchateau M, Namane A, Lopez-Rubio JJ, Pan W, Scherf A.
PMID:22100161 [PubMed - in process]
Organelle segregation into Plasmodium liver stage merozoites.
Stanway RR, Mueller N, Zobiak B, Graewe S, Froehlke U, Zessin PJ, Aepfelbacher M, Heussler VT.
PMID:21801293 [PubMed - in process]
Infection intensity-dependent responses of Anopheles gambiae to the African malaria parasite Plasmodium falciparum.
Mendes AM, Awono-Ambene PH, Nsango SE, Cohuet A, Fontenille D, Kafatos FC, Christophides GK, Morlais I, Vlachou D.
PMID:21844236 [PubMed - indexed for MEDLINE]
October 2011
Associations of multi-locus polymorphisms in an immune network with susceptibility to uncomplicated Plasmodium falciparum malaria in Daraweesh village, Eastern Sudan.
Giha HA, Nasr A, Iriemenam NC, Troye-Blomberg M, Berzins K, Pandey JP, Elghazali G.
PMID:21729768 [PubMed - in process]
Design and evaluation of primaquine-artemisinin hybrids as a multistage antimalarial strategy.
Capela R, Cabal GG, Rosenthal PJ, Gut J, Mota MM, Moreira R, Lopes F, Prudêncio M.
PMID: 21807973 [PubMed - in process]
A recombinant Bacille Calmette-Guérin construct expressing the Plasmodium falciparum circumsporozoite protein enhances dendritic cell activation and primes for circumsporozoite-specific memory cells in BALB/c mice.
Arama C, Waseem S, Fernández C, Assefaw-Redda Y, You L, Rodriguez A, Radoševi? K, Goudsmit J, Kaufmann SH, Reece ST, Troye-Blomberg M.
PMID:21983157 [PubMed - as supplied by publisher]
Discovery of novel alkylated (bis)urea and (bis)thiourea polyamine analogues with potent antimalarial activities.
Verlinden BK, Niemand J, Snyman J, Sharma SK, Beattie RJ, Woster PM, Birkholtz LM.
PMID:21882831 [PubMed - indexed for MEDLINE]
Cytokine gene haplotypes with a potential effect on susceptibility to malaria in sympatric ethnic groups in Mali.
Israelsson E, Maiga B, Kearsley S, Dolo A, Homann MV, Doumbo OK, Troye-Blomberg M, Tornvall P, Berzins K.
PMID:21708291 [PubMed - in process]
A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine.
Porter DW, Thompson FM, BerthoudTK, Hutchings CL, Andrews L, Biswas S, Poulton I, Prieur E, Correa S, Rowland R, Lang T, Williams J, Gilbert SC, Sinden RE, Todryk S, Hill AV.
PMID:21501642 [PubMed - in process]
PbGEST mediates malaria transmission to both mosquito and vertebrate host.
Talman AM, Lacroix C, Marques SR, Blagborough AM, Carzaniga R, Ménard R, Sinden RE.
PMID:21958024 [PubMed - indexed for MEDLINE]
Relation between falciparum malaria and bacteraemia in Kenyan children: a population-based, case-control study and a longitudinal study.
Scott JA, Berkley JA, Mwangi I, Ochola L, Uyoga S, Macharia A, Ndila C, Lowe BS, Mwarumba S, Bauni E, Marsh K, Williams TN.
PMID:21903251 [PubMed - indexed for MEDLINE]
Characterization of a new phosphatase from Plasmodium.
Hills T, Srivastava A, Ayi K, Wernimont AK, Kain K, Waters AP, Hui R, Pizarro JC.
PMID:21689687[PubMed - indexed for MEDLINE]
Plasmodium falciparum NIMA-related kinase Pfnek-1: sex specificity and assessment of essentiality for the erythrocytic asexual cycle.
Dorin-Semblat D, Schmitt S, Semblat JP, Sicard A, Reininger L, Goldring D, Patterson S, Quashie N, Chakrabarti D, Meijer L, Doerig C.
PMID:21757488[PubMed - indexed for MEDLINE]
September 2011
Genetic and transcriptional analysis of phosphoinositide-specific phospholipase C in Plasmodium.
Raabe A, Berry L, Sollelis L, Cerdan R, Tawk L, Vial HJ, Billker O, Wengelnik K.
PMID: 21651909 [PubMed - indexed for MEDLINE]
The requirement for potent adjuvants to enhance the immunogenicity and protective efficacy of protein vaccines can be overcome by prior immunization with a recombinant adenovirus.
de Cassan SC, Forbes EK, Douglas AD, Milicic A, Singh B, Gupta P, Chauhan VS, Chitnis CE, Gilbert SC, Hill AV, Draper SJ.
MID: 21813775 [PubMed - indexed for MEDLINE]
Hostile takeover by Plasmodium: reorganization of parasite and host cell membranes during liver stage egress.
Graewe S, Rankin KE, Lehmann C, Deschermeier C, Hecht L, Froehlke U, Stanway RR, Heussler V.
PMID:21909271 [PubMed - indexed for MEDLINE]
The plasma concentration of the B cell activating factor is increased in children with acute malaria.
Nduati E, Gwela A, Karanja H, Mugyenyi C, Langhorne J, Marsh K, Urban BC.
PMID:21849293 [PubMed - indexed for MEDLINE]
Genetic and transcriptional analysis of phosphoinositide-specific phospholipase C in Plasmodium.
Raabe A, Berry L, Sollelis L, Cerdan R, Tawk L, Vial HJ, Billker O, Wengelnik K.
PMID:21651909 [PubMed - indexed for MEDLINE]
The novel putative transporter NPT1 plays a critical role in early stages of Plasmodium berghei sexual development.
Boisson B, Lacroix C, Bischoff E, Gueirard P, Bargieri DY, Franke-Fayard B, Janse CJ, Ménard R, Baldacci P.
PMID:21752110 [PubMed - in process]
August 2011
Molecular interactions and signaling mechanisms during erythrocyte invasion by malaria parasites.
Gaur D, Chitnis CE.
PMID:21803641[PubMed - indexed for MEDLINE]
Toxoplasma gondii aspartic protease 1 is not essential in tachyzoites.
Polonais V, Shea M, Soldati-Favre D.
PMID: 21616070 [PubMed - indexed for MEDLINE]
TLRs innate immunereceptors and Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) CIDR1?-driven human polyclonal B-cell activation.
Simone O, Bejarano MT, Pierce SK, Antonaci S, Wahlgren M, Troye-Blomberg M, Donati D.
PMID: 21620790 [PubMed - indexed for MEDLINE]
On cytoadhesion of Plasmodium vivax: raison d'être?
Costa FT, Lopes SC, Ferrer M, Leite JA, Martin-Jaular L, Bernabeu M, Nogueira PA, Mourão MP, Fernandez-Becerra C, Lacerda MV, del Portillo H.
PMID: 21881760 [PubMed - indexed for MEDLINE]
Natural haemozoin modulates matrix metalloproteinases and induces morphological changes in human microvascular endothelium.
Prato M, D'Alessandro S, Van den Steen PE, Opdenakker G, Arese P, Taramelli D, Basilico N.
PMID:21707906 [PubMed - indexed for MEDLINE]
FLP/FRT-mediated conditional mutagenesis in pre-erythrocytic stages of Plasmodium berghei.
Lacroix C, Giovannini D, Combe A, Bargieri DY, Späth S, Panchal D, Tawk L, Thiberge S, Carvalho TG, Barale JC, Bhanot P, Ménard R.
PMID:21886105 [PubMed - in process]
PG12, a phospholipid analog with potent antimalarial activity, inhibits Plasmodium falciparum CTP:phosphocholine cytidylyltransferase activity.
González-Bulnes P, Bobenchik AM, Augagneur Y, Cerdan R, Vial HJ, Llebaria A, Ben Mamoun C.
PMID:21705805 [PubMed - indexed for MEDLINE]
Natural haemozoin modulates matrix metalloproteinases and induces morphological changes in human microvascular endothelium.
Prato M, D'Alessandro S, Van den Steen PE, Opdenakker G, Arese P, Taramelli D, Basilico N.
PMID:21707906 [PubMed - indexed for MEDLINE]
July 2011
Targeting TLRs expands the antibody repertoire in response to a malaria vaccine.
Wiley SR, Raman VS, Desbien A, Bailor HR, Bhardwaj R, Shakri AR, Reed SG, Chitnis CE, Carter D.
PMID:21795589[PubMed - indexed for MEDLINE]
Plasmodium vivax: comparison of immunogenicity among proteins expressed in the cell-free systems of Escherichia coli and wheat germ by suspension array assays.
Rui E, Fernandez-Becerra C, Takeo S, Sanz S, Lacerda MV, Tsuboi T, del Portillo HA.
PMID:21756349[PubMed - indexed for MEDLINE] PMCID:PMC3224337
Structural basis for the regulation of cysteine-protease activity by a new class of protease inhibitors in Plasmodium.
Hansen G, Heitmann A, Witt T, Li H, Jiang H, Shen X, Heussler VT, Rennenberg A, Hilgenfeld R.
PMID:21742259 [PubMed - indexed for MEDLINE]
The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19).
Shi J, McIntosh RS, Adame-Gallegos J, Dehal PK, van Egmond M, van de Winkel J, Draper SJ, Forbes EK, Corran PH, Holder AA, Woof JM, Pleass RJ.
PMID:21781305 [PubMed - indexed for MEDLINE]
Plasmodium falciparum-infected erythrocytes and beta-hematin induce partial maturation of human dendritic cells and increase their migratory ability in response to lymphoid chemokines.
Giusti P, Urban BC, Frascaroli G, Albrecht L, Tinti A, Troye-Blomberg M, Varani S.
PMID:21464084 [PubMed - indexed for MEDLINE]
Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation.
Raabe AC, Wengelnik K, Billker O, Vial HJ.
PMID:21518218 [PubMed - indexed for MEDLINE]
Plasmodium falciparum-infected erythrocytes and beta-hematin induce partial maturation of human dendritic cells and increase their migratory ability in response to lymphoid chemokines.
Giusti P, Urban BC, Frascaroli G, Albrecht L, Tinti A, Troye-Blomberg M, Varani S.
PMID:21464084 [PubMed - indexed for MEDLINE]
An effective method to purify Plasmodium falciparum DNA directly from clinical blood samples for whole genome high-throughput sequencing.
Auburn S, Campino S, Clark TG, Djimde AA, Zongo I, Pinches R, Manske M, Mangano V, Alcock D, Anastasi E, Maslen G, Macinnis B, Rockett K, Modiano D, Newbold CI, Doumbo OK, Ouédraogo JB, Kwiatkowski DP.
PMID:21789235 [PubMed - indexed for MEDLINE]
Wide cross-reactivity between Anopheles gambiae and Anopheles funestus SG6 salivary proteins supports exploitation of gSG6 as a marker of human exposure to major malaria vectors in tropical Africa.
Rizzo C, Ronca R, Fiorentino G, Mangano VD, Sirima SB, Nèbiè I, Petrarca V, Modiano D, Arcà B.
PMID:21794142 [PubMed - indexed for MEDLINE]
The generation and evaluation of recombinant human IgA specific for Plasmodium falciparum merozoite surface protein 1-19 (PfMSP1 19)
Shi J, McIntosh RS, Adame-Gallegos J, Dehal PK, van Egmond M, van de Winkel J, Draper SJ, Forbes EK, Corran PH, Holder AA, Woof JM, Pleass RJ.
PMID:21781305 [PubMed - indexed for MEDLINE]
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1.
Barfod L, Dalgaard MB, Pleman ST, Ofori MF, Pleass RJ, Hviid L.
PMID: 21746929 [PubMed - indexed for MEDLINE]
Sickle cell disease and malaria morbidity: a tale with two tails.
Williams TN, Obaro SK.
PMID:21429801 [PubMed - indexed for MEDLINE]
June 2011
Invasion factors are coupled to key signalling events leading to the establishment of infection in apicomplexan parasites.
Santos JM, Soldati-Favre D.
PMID: 21338465
Use of a Selective Inhibitor To Define the Chemotherapeutic Potential of the Plasmodial Hexose Transporter in Different Stages of the Parasite's Life Cycle
Ksenija Slavic, Michael J. Delves, Miguel Prudêncio, Arthur M. Talman, Ursula Straschil, Elvira T. Derbyshire, Zhengyao Xu, Robert E. Sinden, Maria M. Mota, Christophe Morin, Rita Tewari, Sanjeev Krishna, Henry M. Staines
PMCID:PMC3101457
Portugal S, Carret C, Recker M, Armitage AE, Gonçalves LA, Epiphanio S, Sullivan D, Roy C, Newbold CI, Drakesmith H, Mota MM.
PMID: 21572427 [PubMed - indexed for MEDLINE]
Pattern of malaria transmission along the Rahad River basin, Eastern Sudan.
Himeidan YE, Elzaki MM, Kweka EJ, Ibrahim M, Elhassan IM.
PMID: 21679459 [PubMed - indexed for MEDLINE]
The IFN-?-inducible GTPase, Irga6, protects mice against Toxoplasma gondii but not against Plasmodium berghei and some other intracellular pathogens.
Liesenfeld O, Parvanova I, Zerrahn J, Han SJ, Heinrich F, Muñoz M, Kaiser F, Aebischer T, Buch T, Waisman A, Reichmann G, Utermöhlen O, von Stebut E, von Loewenich FD, Bogdan C, Specht S, Saeftel M, Hoerauf A, Mota MM, Könen-Waisman S, Kaufmann SH, Howard JC.
PMID: 21698150 [PubMed - indexed for MEDLINE]
PfCHA is a mitochondrial divalent cation/H+ antiporter in Plasmodium falciparum.
Rotmann A, Sanchez C, Guiguemde A, Rohrbach P, Dave A, Bakouh N, Planelles G, Lanzer M.
PMID: 20487273 [PubMed - indexed for MEDLINE]
Population genetic analysis of Plasmodium falciparum parasites using a customized Illumina GoldenGate genotyping assay.
Campino S, Auburn S, Kivinen K, Zongo I, Ouedraogo JB, Mangano V, Djimde A, Doumbo OK, Kiara SM, Nzila A, Borrmann S, Marsh K, Michon P, Mueller I, Siba P, Jiang H, Su XZ, Amaratunga C, Socheat D, Fairhurst RM, Imwong M, Anderson T, Nosten F, White NJ, Gwilliam R, Deloukas P, MacInnis B, Newbold CI, Rockett K, Clark TG, Kwiatkowski DP.
PMID: 21673999 [PubMed - indexed for MEDLINE]
Drug-resistant malaria: molecular mechanisms and implications for public health.
Petersen I, Eastman R, Lanzer M.
PMID: 21530510 [PubMed - indexed for MEDLINE]
Activation of a PAK-MEK signalling pathway in malaria parasite-infected erythrocytes.
Sicard A, Semblat JP, Doerig C, Hamelin R, Moniatte M, Dorin-Semblat D, Spicer JA, Srivastava A, Retzlaff S, Heussler V, Waters AP, Doerig C.
PMID: 21371233 [PubMed - indexed for MEDLINE]
Transgene optimization, immunogenicity and in vitro efficacy of viral vectored vaccines expressing two alleles of Plasmodium falciparum AMA1.
Biswas S, Dicks MD, Long CA, Remarque EJ, Siani L, Colloca S, Cottingham MG, Holder AA, Gilbert SC, Hill AV, Draper SJ.
PMID: 21698193 [PubMed - indexed for MEDLINE]
Linear amplification for deep sequencing.
Hoeijmakers WA, Bártfai R, Françoijs KJ, Stunnenberg HG.
PMID:21720315 [PubMed - indexed for MEDLINE]
TgROM4 and TgAMA1: a checkpoint in parasite replication.
[Article in French]
Pino P, Soldati-Favre D.
PMID: 21718637 [PubMed - indexed for MEDLINE]
Environmental constraints guide migration of malaria parasites during transmission.
Hellmann JK, Münter S, Kudryashev M, Schulz S, Heiss K, Müller AK, Matuschewski K, Spatz JP, Schwarz US, Frischknecht F.
PMID:21698220 [PubMed - indexed for MEDLINE]
May 2011
Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways.
Baumeister S, Wiesner J, Reichenberg A, Hintz M, Bietz S, Harb OS, Roos DS, Kordes M, Friesen J, Matuschewski K, Lingelbach K, Jomaa H, Seeber F.
PMID:21573242[PubMed - indexed for MEDLINE] PMCID:PMC3087763
Two nucleus-localized CDK-like kinases with crucial roles for malaria parasite erythrocytic replication are involved in phosphorylation of splicing factor.
Agarwal S, Kern S, Halbert J, Przyborski JM, Baumeister S, Dandekar T, Doerig C, Pradel G.
PMID:21312235 [PubMed - indexed for MEDLINE]
The Puf-Family RNA-Binding Protein Puf2 Controls Sporozoite Conversion to Liver Stages in the Malaria Parasite
Katja Müller, Kai Matuschewski, Olivier Silvie
PMCID: PMC3097211
Transition of Plasmodium sporozoites into liver stage-like forms is regulated by the RNA binding protein Pumilio.
Gomes-Santos CS, Braks J, Prudêncio M, Carret C, Gomes AR, Pain A, Feltwell T, Khan S, Waters A, Janse C, Mair GR, Mota MM.
PMID: 21625527 [PubMed - indexed for MEDLINE]
Malaria: modification of the red blood cell and consequences in the human host.
Moxon CA, Grau GE, Craig AG.
PMID: 21623767 [PubMed - as supplied by publisher]
Investigating the host binding signature on the Plasmodium falciparum PfEMP1 protein family.
Janes JH, Wang CP, Levin-Edens E, Vigan-Womas I, Guillotte M, Melcher M, Mercereau-Puijalon O, Smith JD.
PMID: 21573138 [PubMed - indexed for MEDLINE]
April 2011
Parity and placental infection affect antibody responses against Plasmodium falciparum during pregnancy.
Mayor A, Rovira-Vallbona E, Machevo S, Bassat Q, Aguilar R, Quintó L, Jiménez A, Sigauque B, Dobaño C, Kumar S, Singh B, Gupta P, Chauhan VS, Chitnis CE, Alonso PL, Menéndez C.
PMID:21300778[PubMed - indexed for MEDLINE] PMCID:PMC3067565
Association of severe malaria outcomes with platelet-mediated clumping and adhesion to a novel host receptor.
Mayor A, Hafiz A, Bassat Q, Rovira-Vallbona E, Sanz S, Machevo S, Aguilar R, Cisteró P, Sigaúque B, Menéndez C, Alonso PL, Chitnis CE.
PMID:21559373[PubMed - indexed for MEDLINE] PMCID:PMC3084855
Transformation of the rodent malaria parasite Plasmodium chabaudi.
Spence PJ, Cunningham D, Jarra W, Lawton J, Langhorne J, Thompson J.
PMID:21455190[PubMed - indexed for MEDLINE]
The global distribution of the Duffy blood group
Rosalind E. Howes, Anand P. Patil, Frédéric B. Piel, Oscar A. Nyangiri, Caroline W. Kabaria, Peter W. Gething, Peter A. Zimmerman, Céline Barnadas, Cynthia M. Beall, Amha Gebremedhin, Didier Ménard, Thomas N. Williams, David J. Weatherall, Simon I. Hay
PMCID:PMC3074097
Automated counting for Plasmodium falciparum cytoadherence experiments
Douglas Paton, Brian Faragher, Khairul MF Mustaffa, Tadge Szestak, Steve D Barrett, Alister G Craig
PMCID: PMC3094228
Multiple roles for Plasmodium berghei phosphoinositide-specific phospholipase C in regulating gametocyte activation and differentiation
Andreas C Raabe, Kai Wengelnik, Oliver Billker, Henri J Vial
PMCID: PMC3132445
March 2011
Low Anticoagulant Heparin Disrupts Plasmodium falciparum Rosettes in Fresh Clinical Isolates
Anna M. Leitgeb, Karin Blomqvist, Fidelis Cho-Ngwa, Moses Samje, Peter Nde, Vincent Titanji, Mats Wahlgren
PMCID: PMC3042813
Simple flow cytometric detection of haemozoin containing leukocytes and erythrocytes for research on diagnosis, immunology and drug sensitivity testing
Rosangela Frita, Maria Rebelo, Ana Pamplona, Ana M Vigario, Maria M Mota, Martin P Grobusch, Thomas Hänscheid
PMCID: PMC3078904
Antigenic Variation in Plasmodium falciparum Malaria Involves a Highly Structured Switching Pattern
Mario Recker, Caroline O. Buckee, Andrew Serazin, Sue Kyes, Robert Pinches, Zóe Christodoulou, Amy L. Springer, Sunetra Gupta, Chris I. Newbold
PMCID: PMC3048365
Humoral Response to the Anopheles gambiae Salivary Protein gSG6: A Serological Indicator of Exposure to Afrotropical Malaria Vectors
Cinzia Rizzo, Raffaele Ronca, Gabriella Fiorentino, Federica Verra, Valentina Mangano, Anne Poinsignon, Sodiomon Bienvenu Sirima, Issa Nèbiè, Fabrizio Lombardo, Franck Remoue, Mario Coluzzi, Vincenzo Petrarca, David Modiano, Bruno Arcà
PMCID:PMC3060095
Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites
Jannik Fonager, Blandine MD Franke-Fayard, John H Adams, Jai Ramesar, Onny Klop, Shahid M Khan, Chris J Janse, Andrew P Waters
PMCID: PMC3073922
Interethnic differences in antigen-presenting cell activation and TLR responses in Malian children during Plasmodium falciparum malaria.
Arama C, Giusti P, Boström S, Dara V, Traore B, Dolo A, Doumbo O, Varani S, Troye-Blomberg M.
PMID: 21483827 [PubMed - indexed for MEDLINE]
Global Identification of Multiple Substrates for Plasmodium falciparum SUB1, an Essential Malarial Processing Protease
Natalie C. Silmon de Monerri, Helen R. Flynn, Marta G. Campos, Fiona Hackett, Konstantinos Koussis, Chrislaine Withers-Martinez, J. Mark Skehel, Michael J. Blackman
PMCID: PMC3067499
Development of the piggyBac transposable system for Plasmodium berghei and its application for random mutagenesis in malaria parasites
Jannik Fonager, Blandine MD Franke-Fayard, John H Adams, Jai Ramesar, Onny Klop, Shahid M Khan, Chris J Janse, Andrew P Waters
PMCID: PMC3073922
Plasmodium Cysteine Repeat Modular Proteins 3 and 4 are essential for malaria parasite transmission from the mosquito to the host
Bruno Douradinha, Kevin D Augustijn, Sally G Moore, Jai Ramesar, Maria M Mota, Andrew P Waters, Chris J Janse, Joanne Thompson
PMCID: PMC3083381
February 2011
The relevance of non-human primate and rodent malaria models for humans.
Langhorne J, Buffet P, Galinski M, Good M, Harty J, Leroy D, Mota MM, Pasini E, Renia L, Riley E, Stins M, Duffy P.
PMID: 21288352 [PubMed - indexed for MEDLINE]
Analysis of two novel midgut-specific promoters driving transgene expression in Anopheles stephensi mosquitoes.
Nolan T, Petris E, Müller HM, Cronin A, Catteruccia F, Crisanti A.
PMID:21326609 [PubMed - indexed for MEDLINE]
Phosphatidylinositol 3-monophosphate is involved in toxoplasma apicoplast biogenesis.
Tawk L, Dubremetz JF, Montcourrier P, Chicanne G, Merezegue F, Richard V, Payrastre B, Meissner M, Vial HJ, Roy C, Wengelnik K, Lebrun M.
PMID: 21379336 [PubMed - indexed for MEDLINE]
RSpred, a set of Hidden Markov Models to detect and classify the RIFIN and STEVOR proteins of Plasmodium falciparum.
Joannin N, Kallberg Y, Wahlgren M, Persson B.
PMID: 21332983
Specific Receptor Usage in Plasmodium falciparum Cytoadherence Is Associated with Disease Outcome
Lucy B. Ochola, Bethsheba R. Siddondo, Harold Ocholla, Siana Nkya, Eva N. Kimani, Thomas N. Williams, Johnstone O. Makale, Anne Liljander, Britta C. Urban, Pete C. Bull, Tadge Szestak, Kevin Marsh, Alister G. Craig
PMCID: PMC3048392
Targeted Disruption of py235ebp-1: Invasion of Erythrocytes by Plasmodium yoelii Using an Alternative Py235 Erythrocyte Binding Protein
Solabomi A. Ogun, Rita Tewari, Thomas D. Otto, Steven A. Howell, Ellen Knuepfer, Deirdre A. Cunningham, Zhengyao Xu, Arnab Pain, Anthony A. Holder
PMCID:PMC3040676
Antibodies to the Plasmodium falciparum rhoptry protein RAP-2/RSP-2 in relation to anaemia in Cameroonian children.
Awah N, Balogun H, Achidi E, Mariuba LA, Nogueira PA, Orlandi P, Troye-Blomberg M, Gysin J, Berzins K.
PMID:21226723 [PubMed - indexed for MEDLINE]
Plasmodium falciparum reticulocyte binding-like homologue protein 2 (PfRH2) is a key adhesive molecule involved in erythrocyte invasion.
Sahar T, Reddy KS, Bharadwaj M, Pandey AK, Singh S, Chitnis CE, Gaur D.
PMID:21386888[PubMed - indexed for MEDLINE] PMCID:PMC3046117
January 2011
A research agenda to underpin malaria eradication
Alonso PL, Brown G, Arevalo-Herrera M, Binka F, Chitnis C, Collins F, Doumbo OK, Greenwood B, Hall BF, Levine MM, Mendis K, Newman RD, Plowe CV, Rodríguez MH, Sinden R, Slutsker L, Tanner M.
PMID:21311579[PubMed - indexed for MEDLINE] PMCID:PMC3026687
Strain-specific spleen remodelling in Plasmodium yoelii infections in Balb/c mice facilitates adherence and spleen macrophage-clearance escape.
Martin-Jaular L, Ferrer M, Calvo M, Rosanas-Urgell A, Kalko S, Graewe S, Soria G, Cortadellas N, Ordi J, Planas A, Burns J, Heussler V, del Portillo HA.
PMID:20923452[PubMed - indexed for MEDLINE] PMCID:PMC3228402
A research agenda for malaria eradication: basic science and enabling technologies.
malERA Consultative Group on Basic Science and Enabling Technologies.
Collaborators (31) Amino R, Bassat Q, Baum J, Billker O, Bogyo M, Bousema T, Christophides G, Deitsch K, Dinglasan R, Djimde A, Duraisingh M, Dzinjalamala F, Happi C, Heussler V, Kramarik J, de Koning-Ward T, Lacerda M, Laufer M, Lim P, Llinas M, McGovern V, Martinez-Barnetche J, Mota MM, Mueller I, Okumu F, Rasgon J, Serazin A, Sharma P, Sinden R, Wirth D, Gilberger T.
PMID:21311584[PubMed - indexed for MEDLINE] PMCID:PMC3026698
An essential Aurora-related kinase transiently associates with spindle pole bodies during Plasmodium falciparum erythrocytic schizogony.
Reininger L, Wilkes JM, Bourgade H, Miranda-Saavedra D, Doerig C.
PMID:21166904[PubMed - indexed for MEDLINE] PMCID:PMC3025120
Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.
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Genetic predisposition favors the acquisition of stable artemisinin resistance in malaria parasites.
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Strain-specific spleen remodelling in Plasmodium yoelii infections in Balb/c mice facilitates adherence and spleen macrophage-clearance escape.
Martin-Jaular L, Ferrer M, Calvo M, Rosanas-Urgell A, Kalko S, Graewe S, Soria G, Cortadellas N, Ordi J, Planas A, Burns J, Heussler V, del Portillo HA.
PMID:20923452[PubMed - indexed for MEDLINE] PMCID:PMC3228402
A genotype and phenotype database of genetically modified malaria-parasites.
Janse CJ, Kroeze H, van Wigcheren A, Mededovic S, Fonager J, Franke-Fayard B, Waters AP, Khan SM.
PMID:20663715[PubMed - indexed for MEDLINE]
Symmetrical choline-derived dications display strong anti-kinetoplastid activity
Hasan M. S. Ibrahim, Mohammed I. Al-Salabi, Nasser El Sabbagh, Neils B. Quashie, Abdulsalam A. M. Alkhaldi, Roger Escale, Terry K. Smith, Henri J. Vial, Harry P. de Koning
PMCID: PMC3001849
Lactase persistence genotypes and malaria susceptibility in Fulani of Mali
A Inkeri Lokki, Irma Järvelä, Elisabeth Israelsson, Bakary Maiga, Marita Troye-Blomberg, Amagana Dolo, Ogobara K Doumbo, Seppo Meri, Ville Holmberg
PMCID: PMC3031279
EU-funded malaria research under the 6th and 7th Framework Programmes for research and technological development
Andreas Holtel, Marita Troye-Blomberg, Inmaculada Penas-Jimenez
PMCID: PMC3031276
A research agenda to underpin malaria eradication.
Alonso PL, Brown G, Arevalo-Herrera M, Binka F, Chitnis C, Collins F, Doumbo OK, Greenwood B, Hall BF, Levine MM, Mendis K, Newman RD, Plowe CV, Rodríguez MH, Sinden R, Slutsker L, Tanner M.
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var gene transcription and PfEMP1 expression in the rosetting and cytoadhesive Plasmodium falciparum clone FCR3S1.2.
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Allelic diversity of the Plasmodium falciparum erythrocyte membrane protein 1 entails variant-specific red cell surface epitopes.
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Antibodies to plant-produced Plasmodium falciparum sexual stage protein Pfs25 exhibit transmission blocking activity.
Farrance CE, Chichester JA, Musiychuk K, Shamloul M, Rhee A, Manceva SD, Jones RM, Mamedov T, Sharma S, Mett V, Streatfield SJ, Roeffen W, van de Vegte-Bolmer M, Sauerwein RW, Wu Y, Muratova O, Miller L, Duffy P, Sinden R, Yusibov V.
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Janse CJ, Kroeze H, van Wigcheren A, Mededovic S, Fonager J, Franke-Fayard B, Waters AP, Khan SM.
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A research agenda for malaria eradication: basic science and enabling technologies.
malERA Consultative Group on Basic Science and Enabling Technologies.
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A research agenda for malaria eradication: modeling.
malERA Consultative Group on Modeling.
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A research agenda for malaria eradication: drugs.
malERA Consultative Group on Drugs.
PMID: 21311580 [PubMed - indexed for MEDLINE]
A research agenda for malaria eradication: vaccines.
malERA Consultative Group on Vaccines.
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A research agenda for malaria eradication: vector control.
malERA Consultative Group on Vector Control.
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Pharmacokinetic properties and metabolism of a new potent antimalarial N-alkylamidine compound, M64, and its corresponding bioprecursors.
Margout D, Gattacceca F, Moarbess G, Wein S, Tran van Ba C, Le Pape S, Berger O, Escale R, Vial HJ, Bressolle FM.
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Plasmodium falciparum liver stage antigen-1 is cross-linked by tissue transglutaminase.
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PMID:21255444[PubMed - indexed for MEDLINE] PMCID:PMC3037345
Intramembrane cleavage of AMA1 triggers Toxoplasma to switch from an invasive to a replicative mode.
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